Understanding how the brain learns to recognize complex sounds
Official title: Neural dynamics in auditory cortex during implicit learning of complex sounds
Funded at Johns Hopkins University · NIH-11121297 · Data updated 2026-11-12
This study is exploring how the brains of awake mice naturally learn to recognize different sounds without even trying, which could help us understand how our own brains process and learn about sounds.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project start | April 1, 2025 |
| Project end | March 31, 2028 |
| Funding year | 2025 |
| Award (this year) | $193,750 |
| NIH project number | 1R21DC021520-01A1 |
| Project ID | NIH-11121297 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for benefiting from this research would include individuals with central auditory processing disorders or those experiencing difficulties in sound recognition.
✕Less likely to help
Patients with no auditory processing issues or those who are not affected by sound recognition challenges may not receive direct benefits from this research.
What this research studies
This research investigates how the brain's auditory cortex processes and learns to recognize complex sounds without conscious effort, a process known as implicit learning. Using advanced techniques like two-photon calcium imaging and holographic optogenetic stimulation, the study examines the neural responses of awake mice to various sound sequences. By analyzing how different types of neurons respond to repeated sounds, the research aims to map the neural circuits involved in auditory learning. This could provide insights into the fundamental mechanisms of auditory perception and learning.
Why it matters
Potential benefit: If successful, this research could enhance our understanding of auditory processing, potentially leading to improved treatments for auditory processing disorders.
How similar studies have gone: While the specific approach of mapping neural circuits for implicit learning in the auditory cortex is novel, similar studies have shown success in understanding auditory processing mechanisms.
Where this research is happening
-
Johns Hopkins University
Baltimore, United States Active
Researchers
- Principal investigator: Kang, Hijee — Johns Hopkins University
- Study coordinator: Kang, Hijee
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.