NIH-funded research U01 cooperative agreement

Understanding how the brain adapts after visual damage

Official title: Circuit and Computational Principles of Plasticity Following Damage

Funded at University of Rochester · NIH-10865370 · Data updated 2026-11-12

This study is looking at how the brain can adapt and recover after damage to the part that helps us see, and it's for anyone interested in understanding how vision can improve after an injury.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionUniversity of Rochester
NIH-funded
Lab location1 site (Rochester, United States)
Project startMay 1, 2025
Project endApril 30, 2028
Funding year2025
Award (this year)$1,319,879
NIH project number1U01NS136338-01
Project IDNIH-10865370 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research include individuals who have experienced damage to the primary visual cortex due to injury or stroke.

Less likely to help

Patients with intact visual processing capabilities or those with damage outside the primary visual cortex may not benefit from this research.

What this research studies

This research investigates how the brain reorganizes itself after damage to the primary visual cortex, which is crucial for processing visual information. By studying both human and animal models, the project aims to uncover the mechanisms behind functional recovery and plasticity in the visual system. The researchers will use advanced techniques to analyze how visual perception can be partially restored following injury, providing insights into the brain's adaptive capabilities.

Why it matters

Potential benefit: If successful, this research could lead to new therapies that enhance recovery of visual functions in patients with brain injuries.

How similar studies have gone: Previous research has shown promising results in understanding brain plasticity, suggesting that this approach could yield valuable insights.

Where this research is happening

  • University of Rochester
    Rochester, United States
    Active

Researchers

  • Principal investigator: Huxlin, Krystel R — University of Rochester
  • Study coordinator: Huxlin, Krystel R

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.