Understanding how teeth develop and grow in size
Official title: Identification of the factors underlying tooth field size and competency
Funded at University of Florida · NIH-11059933 · Data updated 2026-11-12
This study is looking into how our genes and cells help shape our teeth, with the hope of finding ways to grow new teeth in the lab that could be used for people who need them.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Florida NIH-funded |
| Lab location | 1 site (Gainesville, United States) |
| Project start | April 1, 2024 |
| Project end | March 31, 2027 |
| Funding year | 2025 |
| Award (this year) | $248,961 |
| NIH project number | 5R00DE031017-04 |
| Project ID | NIH-11059933 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adults who have experienced tooth loss or are interested in dental regeneration techniques.
✕Less likely to help
Patients with healthy teeth and no history of dental issues may not benefit from this research.
What this research studies
This research investigates the genetic and cellular factors that influence the development and size of tooth fields in adults. By analyzing gene expression and signaling pathways, the study aims to identify the specific cell types involved in tooth formation and their potential to create new teeth. The findings could lead to innovative methods for developing lab-grown teeth that can be successfully implanted in patients. This research is particularly focused on the biological processes that govern tooth development during early life stages.
Why it matters
Potential benefit: If successful, this research could lead to new treatments for tooth loss, allowing for the creation of lab-grown teeth that can be implanted in patients.
How similar studies have gone: Previous research has shown promise in understanding tooth development, but this specific approach to creating lab-made teeth is relatively novel.
Where this research is happening
-
University of Florida
Gainesville, United States Active
Researchers
- Principal investigator: Square, Tyler — University of Florida
- Study coordinator: Square, Tyler
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.