NIH-funded research R01 grant

Understanding how spinal movement issues affect recovery from acute low back pain

Official title: Significance of Spinal Movement Impairments in Acute Low Back Pain

Funded at Washington University · NIH-11043348 · Data updated 2026-11-12

This study is looking at how certain movement issues in the spine affect how quickly people with recent low back pain recover, and it's for adults aged 18-60 who are dealing with this type of pain for the first time.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionWashington University
NIH-funded
Lab location1 site (Saint Louis, United States)
Project startApril 14, 2023
Project endFebruary 29, 2028
Funding year2025
Award (this year)$626,935
NIH project number5R01HD108240-03
Project IDNIH-11043348 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are adults aged 18-60 who are experiencing acute low back pain without a prior history of chronic low back pain.

Less likely to help

Patients with a history of chronic low back pain or those outside the age range of 18-60 may not benefit from this research.

What this research studies

This research investigates the impact of specific spinal movement impairments on the recovery process of individuals experiencing acute low back pain (LBP). By enrolling 212 participants aged 18-60 who have acute LBP without a history of chronic pain, the study aims to identify how these impairments influence recovery and function. Participants will undergo clinical examinations and complete self-report surveys to gather data on their pain history, psychosocial factors, and treatment experiences. The findings could help develop targeted treatments for those suffering from acute LBP.

Why it matters

Potential benefit: If successful, this research could lead to improved treatment strategies that enhance recovery and reduce the long-term impact of acute low back pain.

How similar studies have gone: Previous research has shown that addressing spinal movement impairments can significantly impact recovery in chronic low back pain, suggesting potential for success in this acute setting.

Where this research is happening

  • Washington University
    Saint Louis, United States
    Active

Researchers

  • Principal investigator: Vandillen, Linda R — Washington University
  • Study coordinator: Vandillen, Linda R

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.