Understanding how sleep problems affect thinking in older adults
Noradrenergic Dysregulation, Sleep and Cognition in Older Adults with Insomnia
This study is looking at how trouble sleeping might affect thinking and memory in older adults, and it wants to find out if changes in the body's nervous system play a role in this connection.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Northwestern University at Chicago NIH-funded |
| Lab location | 1 site (Chicago, United States) |
| Project ID | NIH-10804350 on NIH RePORTER |
What this research studies
This research investigates the connection between insomnia, sleep quality, and cognitive function in older adults. It focuses on how changes in the autonomic nervous system, particularly noradrenergic activity, may influence sleep and cognitive abilities. By measuring sleep patterns and cognitive performance, the study aims to uncover the biological mechanisms linking insomnia to cognitive decline. Participants will undergo assessments to evaluate their sleep quality and cognitive function over time.
Who could benefit from this research
Good fit: Ideal candidates for this research are older adults aged 65 and above who experience insomnia.
Not a fit: Patients who do not have insomnia or are younger than 65 years old may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for improving sleep and cognitive health in older adults, potentially reducing the risk of Alzheimer's disease-related dementias.
How similar studies have performed: Previous research has shown promising results in understanding the relationship between sleep quality and cognitive function in older adults, suggesting that this approach may yield valuable insights.
Where this research is happening
Chicago, United States
- Northwestern University at Chicago — Chicago, United States (Active)
Researchers
- Principal investigator: Zee, Phyllis C. — Northwestern University at Chicago
- Study coordinator: Zee, Phyllis C.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.