Understanding how real-world lung cancer screening works across diverse populations
Official title: Learning about the effectiveness of lung cancer screening in real-world target populations
Funded at Dartmouth College · NIH-11394614 · Data updated 2026-11-12
A real-world study to see how lung cancer screening affects people in everyday clinical settings, beyond highly controlled trials.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Dartmouth College NIH-funded |
| Lab location | 1 site (Hanover, United States) |
| Project start | January 1, 2024 |
| Project end | August 31, 2028 |
| Funding year | 2026 |
| Award (this year) | $249,000 |
| NIH project number | 5R00CA287059-04 |
| Project ID | NIH-11394614 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates include adults at risk for lung cancer who would be considered for screening in real-world healthcare settings.
✕Less likely to help
Patients who are not current or past smokers or who are not in populations considered for screening may see limited direct benefit.
What this research studies
This project will combine data from claims, screening registries, and prospective studies to understand how screening performs in diverse populations outside of trial conditions. It aims to develop methods that give results with clear, causal interpretation for real-world groups and to transport findings from existing data to nationally representative populations. The goal is to find strategies that could reduce lung cancer deaths when screening is implemented in routine practice. The work will be led by Dartmouth College and collaborators, focusing on improving evidence used to guide screening decisions. The study will emphasize generalizability and real-world applicability of screening recommendations.
Why it matters
Potential benefit: If successful, the project could improve how lung cancer screening is applied in everyday healthcare, potentially reducing mortality through better-targeted and more effective screening.
How similar studies have gone: Prior trials like NLST provide a foundation, but this project focuses on real-world applicability and causal interpretation, which is a newer approach with promising potential.
Where this research is happening
-
Dartmouth College
Hanover, United States Active
Researchers
- Principal investigator: Robertson, Sarah E — Dartmouth College
- Study coordinator: Robertson, Sarah E
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.