Understanding how rare retinal cells affect vision in primates
Official title: Linking rare primate ganglion cells to downstream visual functions
Funded at University of Rochester · NIH-11163602 · Data updated 2026-11-12
This study is looking at special types of cells in the eye that help us see, using advanced imaging techniques on living monkeys, to better understand how they work and how this knowledge might help improve vision for people with eye problems.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Rochester NIH-funded |
| Lab location | 1 site (Rochester, United States) |
| Project start | September 1, 2023 |
| Project end | August 31, 2027 |
| Funding year | 2024 |
| Award (this year) | $249,001 |
| NIH project number | 4R00EY035323-03 |
| Project ID | NIH-11163602 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with visual impairments or conditions affecting retinal function.
✕Less likely to help
Patients with visual impairments not related to retinal ganglion cell dysfunction may not benefit from this research.
What this research studies
This research investigates the role of rare types of retinal ganglion cells (RGCs) in visual processing by using advanced imaging techniques in living macaques. The study employs non-invasive methods to visualize and classify these rare RGCs, which are crucial for understanding how they contribute to vision. By combining calcium imaging and fluorescence adaptive optics scanning light ophthalmoscopy (FAOSLO), researchers aim to explore the functions of these cells and their impact on visual behaviors. The findings could provide insights into the mechanisms of vision and potential treatments for visual impairments.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and treatment options for visual disorders related to retinal ganglion cell dysfunction.
How similar studies have gone: Previous research has shown success in using advanced imaging techniques to study retinal cells, indicating a promising approach in this area.
Where this research is happening
-
University of Rochester
Rochester, United States Active
Researchers
- Principal investigator: Patterson, Sara S — University of Rochester
- Study coordinator: Patterson, Sara S
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.