Understanding how proteins are transported within cells
Official title: Mechanisms of vesicle trafficking and kinesin regulation
Funded at Rensselaer Polytechnic Institute · NIH-10842590 · Data updated 2026-11-12
This study is looking at how certain proteins move to the right spots inside cells, which is important for how cells grow and work, and it's for anyone interested in understanding the basics of how our cells communicate and function better.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Rensselaer Polytechnic Institute NIH-funded |
| Lab location | 1 site (Troy, United States) |
| Project start | July 1, 2024 |
| Project end | June 30, 2029 |
| Funding year | 2024 |
| Award (this year) | $398,023 |
| NIH project number | 1R35GM153259-01 |
| Project ID | NIH-10842590 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with conditions that involve cellular communication and signaling disorders, particularly those affecting the nervous system.
✕Less likely to help
Patients with conditions unrelated to cellular transport mechanisms or those not involving cellular signaling may not benefit from this research.
What this research studies
This research investigates the mechanisms by which proteins are transported to specific locations within cells, which is crucial for various cellular functions such as development and metabolism. The team will utilize advanced tools and techniques, including live cell imaging and primary neuron cultures, to explore how kinesins, a type of motor protein, are recruited to transport vesicles. By identifying the molecular links between cargo sorting and kinesin recruitment, the research aims to uncover fundamental processes that govern cellular communication and function.
Why it matters
Potential benefit: If successful, this research could lead to new insights into cellular processes that may improve understanding and treatment of diseases related to cellular dysfunction.
How similar studies have gone: While the specific approach of this research is novel, similar studies have shown promise in understanding cellular transport mechanisms.
Where this research is happening
-
Rensselaer Polytechnic Institute
Troy, United States Active
Researchers
- Principal investigator: Bentley, Marvin — Rensselaer Polytechnic Institute
- Study coordinator: Bentley, Marvin
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.