Understanding how nerves interact with tissues during face development

Trigeminal nerve-target tissue interactions during craniofacial development

NIH-funded research Univ of Maryland, College Park · NIH-11032025

This study looks at how certain nerves in the head work with different tissues to shape the face and head, hoping to find out why some babies are born with facial differences, so we can better prevent or treat these conditions.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionUniv of Maryland, College Park NIH-funded
Lab location1 site (College Park, United States)
Project IDNIH-11032025 on NIH RePORTER

What this research studies

This research investigates the interactions between cranial nerves and various tissues during the development of the head and face. It aims to understand how these interactions can lead to craniofacial abnormalities, which are significant contributors to birth defects. By studying the trigeminal nerve and its role in the development of facial structures, the research seeks to uncover the mechanisms behind proper tissue formation and the implications of nerve signaling. This holistic approach could provide insights into preventing or treating craniofacial disorders.

Who could benefit from this research

Good fit: Ideal candidates for this research include expectant parents with a family history of craniofacial anomalies or those who have been diagnosed with conditions affecting craniofacial development.

Not a fit: Patients with established craniofacial anomalies who are seeking surgical correction may not benefit directly from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved prevention and treatment strategies for craniofacial birth defects.

How similar studies have performed: Previous studies have shown promising results in understanding nerve-tissue interactions in craniofacial development, indicating that this approach has potential for significant advancements.

Where this research is happening

College Park, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.