Understanding how mortalin affects thyroid cancer
The Role of Mortalin in Thyroid Cancer
This study is looking at a protein called mortalin in thyroid cancer to see how it helps cancer cells survive and manage energy, with the hope that finding ways to target this protein could lead to new treatments for patients.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Medical College of Wisconsin NIH-funded |
| Lab location | 1 site (Milwaukee, United States) |
| Project ID | NIH-10884160 on NIH RePORTER |
What this research studies
This research investigates the role of a protein called mortalin in thyroid cancer, focusing on how it helps tumor cells manage their energy and survive under stress. The team aims to uncover the mechanisms that lead to increased levels of mortalin in these cancer cells and explore whether targeting this protein could be a new way to treat thyroid cancer. By analyzing data from previous studies and conducting experiments on thyroid tumor cell lines, they hope to identify potential therapeutic strategies that could lead to improved outcomes for patients.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with thyroid cancer who may benefit from novel therapeutic approaches.
Not a fit: Patients with non-cancerous thyroid conditions or those with advanced thyroid cancer that has not responded to other treatments may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatment options for thyroid cancer patients by targeting metabolic processes that support tumor growth.
How similar studies have performed: Previous research has shown promising results in targeting metabolic processes in cancer treatment, suggesting that this approach may hold potential for thyroid cancer as well.
Where this research is happening
Milwaukee, United States
- Medical College of Wisconsin — Milwaukee, United States (Active)
Researchers
- Principal investigator: Park, Jong-in — Medical College of Wisconsin
- Study coordinator: Park, Jong-in
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.