Understanding how mechanical forces affect diabetic wound healing
Official title: Elucidating the role of mechanical forces in diabetic wound healing
Funded at Stanford University · NIH-11380664 · Data updated 2026-11-12
This NIH grant supports research to learn how physical forces influence healing of diabetes-related skin wounds, with the goal of improving outcomes for people who have diabetes.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Stanford University NIH-funded |
| Lab location | 1 site (Stanford, United States) |
| Project start | July 1, 2023 |
| Project end | June 19, 2027 |
| Funding year | 2026 |
| Award (this year) | $150,110 |
| NIH project number | 5K08DK134871-04 |
| Project ID | NIH-11380664 on NIH RePORTER |
Who could benefit from this research
✓Could help
Patients with diabetes who develop chronic skin wounds may benefit from future therapies arising from this work.
✕Less likely to help
Direct benefits may not be available during the study, but findings could lead to future treatments.
What this research studies
If you have diabetes, your wounds heal differently because of blood vessel problems and the mechanical stress on wounds. The project uses advanced single-cell technologies to study how different cell types respond to diabetes and mechanical forces during healing. Researchers will map how these factors change cell populations over time to identify potential targets for therapies. The work is performed at Stanford and aims to translate findings into better treatments to prevent chronic wounds and amputations.
Why it matters
Potential benefit: Better understanding of why diabetic wounds don’t heal and development of targeted therapies to promote healing and prevent complications.
How similar studies have gone: Prior work has shown that vascular and mechanoresponsive cells influence healing, with ongoing but still exploratory advances in single-cell approaches.
Where this research is happening
-
Stanford University
Stanford, United States Active
Researchers
- Principal investigator: Januszyk, Michael — Stanford University
- Study coordinator: Januszyk, Michael
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.