Understanding how integrins affect brain development and function
Integrin Functions in Shaping Cortical Circuits
This study is looking at how a specific protein called integrin beta 3 affects brain development and function, which could help us understand and improve treatments for conditions like autism.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | James Madison University NIH-funded |
| Lab location | 1 site (Harrisonburg, United States) |
| Project ID | NIH-10831104 on NIH RePORTER |
What this research studies
This research investigates the role of integrins, specifically integrin beta 3, in the development and function of the cerebral cortex, which is crucial for diagnosing and treating neurodevelopmental disorders like autism. The approach involves studying the anatomical, physiological, and behavioral impacts of these proteins on brain circuitry in living organisms. By utilizing advanced techniques, the research aims to clarify how these cell adhesion molecules influence brain development and connectivity, potentially leading to new insights into autism spectrum disorders.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research are individuals diagnosed with autism spectrum disorder, especially those in early developmental stages.
Not a fit: Patients with neurodevelopmental disorders unrelated to integrin functions or those outside the autism spectrum may not receive benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnostic and therapeutic strategies for neurodevelopmental disorders, particularly autism.
How similar studies have performed: Previous research has shown promising results in understanding the role of cell adhesion molecules in neurodevelopment, suggesting that this approach could yield valuable insights.
Where this research is happening
Harrisonburg, United States
- James Madison University — Harrisonburg, United States (Active)
Researchers
- Principal investigator: Vidal, George — James Madison University
- Study coordinator: Vidal, George
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.