Understanding how immune cells affect bone healing in gum disease
Osteoimmunology of Retarded Bone Regeneration in Periodontitis
This study is looking into why people with gum disease have a harder time healing their bones, and it needs patients to help by sharing samples or information so researchers can find out how certain proteins and immune cells affect bone recovery.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Nova Southeastern University NIH-funded |
| Lab location | 1 site (Fort Lauderdale-Davie, UNITED STATES) |
| Project ID | NIH-11179706 on NIH RePORTER |
What this research studies
This research investigates the reasons behind slow bone healing in patients with periodontitis, a serious gum disease. It focuses on specific proteins that may disrupt the natural process of bone regeneration after treatment. By examining the interactions between immune cells and bone cells, the study aims to uncover the molecular mechanisms that lead to impaired healing. Patients may be involved in providing samples or data to help identify these processes and potential therapeutic targets.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults over 21 years old who have been diagnosed with periodontitis.
Not a fit: Patients with other types of dental issues unrelated to periodontitis may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that enhance bone regeneration in patients with periodontitis.
How similar studies have performed: Previous research has shown that understanding the immune response can lead to breakthroughs in treating bone regeneration issues, suggesting this approach has potential.
Where this research is happening
Fort Lauderdale-Davie, UNITED STATES
- Nova Southeastern University — Fort Lauderdale-Davie, United States (Active)
Researchers
- Principal investigator: Kawai, Toshihisa — Nova Southeastern University
- Study coordinator: Kawai, Toshihisa
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.