Understanding how gliding membranes develop in sugar gliders
Official title: The cellular mechanisms and molecular evolution of mammalian gliding membrane outgrowth
Funded at Princeton University · NIH-11068152 · Data updated 2026-11-12
This study looks at how sugar gliders develop their special gliding membranes by exploring the signals that affect their cells and genes during early growth, which could help us understand similar processes in other animals.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Princeton University NIH-funded |
| Lab location | 1 site (Princeton, UNITED STATES) |
| Project start | November 1, 2024 |
| Project end | October 31, 2027 |
| Funding year | 2024 |
| Award (this year) | $32,974 |
| NIH project number | 1F31HD117557-01 |
| Project ID | NIH-11068152 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation or benefit from this research would be individuals with genetic or developmental disorders linked to cellular signaling and growth processes.
✕Less likely to help
Patients with conditions unrelated to cellular development or signaling mechanisms may not receive any benefit from this research.
What this research studies
This research investigates the cellular and molecular processes involved in the development of gliding membranes in sugar gliders. By examining how biochemical and mechanical signals influence gene expression and cellular behavior during embryonic development, the study aims to uncover the underlying mechanisms that lead to developmental defects. The research employs mathematical modeling and in vitro assays to analyze cell density and gene regulatory networks that contribute to the formation of these membranes. Insights gained from this work could enhance our understanding of similar processes in other mammals.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding of developmental defects and potential therapeutic strategies for related conditions in humans.
How similar studies have gone: While this research explores novel aspects of developmental biology, similar studies have shown success in understanding cellular mechanisms in other model organisms.
Where this research is happening
-
Princeton University
Princeton, United States Active
Researchers
- Principal investigator: Sen, Harsha — Princeton University
- Study coordinator: Sen, Harsha
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.