Understanding how early embryos control gene activity
Official title: Transcriptional potency in early embryos
Funded at College of Staten Island · NIH-10874795 · Data updated 2026-11-12
This study is looking at how early embryos control which genes are turned on or off, helping us understand how they grow and develop into different types of cells.
Quick facts
| Grant type | R15 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | College of Staten Island NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | September 23, 2024 |
| Project end | August 31, 2027 |
| Funding year | 2024 |
| Award (this year) | $378,123 |
| NIH project number | 1R15HD115134-01 |
| Project ID | NIH-10874795 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation or benefit from this research are individuals under 21 years old, particularly those interested in developmental biology or genetic research.
✕Less likely to help
Patients who are not involved in developmental processes or who are over 21 years old may not receive direct benefits from this research.
What this research studies
This research investigates the mechanisms that determine how early embryos regulate gene activity. By examining the relationships between DNA accessibility, nucleosome behavior, and transcription factors, the study aims to uncover how certain DNA sequences can influence gene expression in embryos. Using advanced genomic techniques, researchers will identify transcriptional regulatory elements that play a crucial role in this process. The findings could enhance our understanding of embryonic development and cell differentiation.
Why it matters
Potential benefit: If successful, this research could lead to new insights into developmental biology and potential therapeutic strategies for conditions related to gene regulation.
How similar studies have gone: Other research has shown promising results in understanding gene regulation mechanisms, making this approach both relevant and potentially impactful.
Where this research is happening
-
College of Staten Island
New York, United States Active
Researchers
- Principal investigator: Arenas-Mena, Cesar — College of Staten Island
- Study coordinator: Arenas-Mena, Cesar
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.