Improving computational resources for studying cancer-related DNA structures
Official title: Acquisition of an Additional Mixed CPU/GPU Computational Node at the CUNY HPCC
Funded at College of Staten Island · NIH-10801797 · Data updated 2026-11-12
This study is working to improve computer technology at the City University of New York to help scientists better understand how changes in DNA can lead to cancer, while also giving students hands-on experience with advanced tools in chemistry and biochemistry.
Quick facts
| Grant type | R15 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | College of Staten Island NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | June 1, 2022 |
| Project end | May 31, 2026 |
| Funding year | 2023 |
| Award (this year) | $91,149 |
| NIH project number | 3R15GM146228-01S1 |
| Project ID | NIH-10801797 on NIH RePORTER |
Who could benefit from this research
✓Could help
Patients with cancers related to genetic mutations and those interested in the molecular biology of cancer may benefit from the findings of this research.
✕Less likely to help
Patients with non-malignant conditions or those not affected by genetic alterations in nucleosomes may not receive direct benefits from this research.
What this research studies
This research aims to enhance the computational capabilities at the City University of New York's High Performance Computing Center to support advanced studies on the structure and dynamics of nucleosomes, which are critical in understanding cancer-related genetic mutations. By acquiring additional computational nodes equipped with GPUs, the project will facilitate detailed simulations that help characterize how DNA and its modifications contribute to malignancies. The research also provides valuable training opportunities for undergraduate and graduate students in fields like Chemistry and Biochemistry, allowing them to engage with cutting-edge technology in molecular biophysics.
Why it matters
Potential benefit: If successful, this research could lead to a better understanding of the molecular mechanisms behind cancer, potentially informing new therapeutic strategies.
How similar studies have gone: Previous research utilizing advanced computational methods in molecular biophysics has shown promise in elucidating complex biological processes, suggesting that this approach could yield significant insights.
Where this research is happening
-
College of Staten Island
New York, United States Active
Researchers
- Principal investigator: Loverde, Sharon Marie — College of Staten Island
- Study coordinator: Loverde, Sharon Marie
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.