Understanding how different people respond to COVID-19
Official title: Diversity and Determinants of the Immune-Inflammatory Response to SARS-CoV-2
Funded at Cedars-Sinai Medical Center · NIH-10688386 · Data updated 2026-11-12
This study is looking at how different people's immune systems respond to the COVID-19 virus, especially those who might get sicker, to help find better ways to treat and prevent the illness, and it involves tracking the health of patients and healthcare workers over time.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Cedars-Sinai Medical Center NIH-funded |
| Lab location | 1 site (Los Angeles, United States) |
| Project start | September 30, 2020 |
| Project end | August 31, 2025 |
| Funding year | 2022 |
| Award (this year) | $1,738,155 |
| NIH project number | 4U54CA260591-02 |
| Project ID | NIH-10688386 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates include individuals with confirmed or suspected COVID-19 and healthcare workers involved in their treatment.
✕Less likely to help
Patients who are not at risk for severe COVID-19 outcomes or those without a confirmed or suspected diagnosis may not benefit from this research.
What this research studies
This research investigates the immune and inflammatory responses to the SARS-CoV-2 virus among diverse populations, particularly those at higher risk for severe outcomes. It involves collecting and analyzing data from patients with confirmed or suspected COVID-19 and healthcare workers involved in their care. By examining the course of illness, recovery, and potential immunity, the study aims to provide insights that could improve treatment and prevention strategies for COVID-19. Participants will be part of a longitudinal study that tracks their health over time.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and management of COVID-19, particularly for vulnerable populations.
How similar studies have gone: Other research has shown success in understanding immune responses to viral infections, making this approach promising.
Where this research is happening
-
Cedars-Sinai Medical Center
Los Angeles, United States Active
Researchers
- Principal investigator: Figueiredo, Jane C. — Cedars-Sinai Medical Center
- Study coordinator: Figueiredo, Jane C.
Related research
Other NIH-funded projects on the same topics.
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Understanding the immune response to COVID-19
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.