NIH-funded research NIH-funded research

Understanding how different brain regions communicate during decision-making

Official title: P4: Multiregion interactions

Funded at Princeton University · NIH-10900688 · Data updated 2026-11-12

This study is looking at how different parts of the brain work together when we remember things and make decisions, and it aims to help people by understanding how brain activity changes with different tasks.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionPrinceton University
NIH-funded
Lab location1 site (Princeton, UNITED STATES)
Project startAugust 8, 2023
Project endJune 30, 2028
Funding year2024
Award (this year)$685,433
NIH project number5U19NS132720-02
Project IDNIH-10900688 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for participation are individuals with cognitive impairments or those interested in understanding decision-making processes.

Less likely to help

Patients with no cognitive issues or those not engaged in decision-making tasks may not benefit from this research.

What this research studies

This research investigates the interactions between various brain regions involved in working memory and decision-making. By utilizing advanced recording technologies, the project aims to capture how information flows between these regions and how this communication changes based on different tasks. Patients may benefit from insights gained through large-scale recordings and targeted experiments that explore the effects of neural activity perturbations. The research combines innovative methodologies to provide a comprehensive understanding of brain function.

Why it matters

Potential benefit: If successful, this research could lead to improved treatments for cognitive disorders by enhancing our understanding of brain interactions.

How similar studies have gone: Other research has shown promise in understanding brain region interactions, but this approach is innovative and aims to provide new insights.

Where this research is happening

  • Princeton University
    Princeton, United States
    Active

Researchers

  • Principal investigator: Witten, Ilana — Princeton University
  • Study coordinator: Witten, Ilana

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.