Understanding how Chlamydia interacts with human cells
Official title: Characterizing the Redoxome of Chlamydia and Its Host Cell
Funded at University of Nebraska Medical Center · NIH-10909320 · Data updated 2026-11-12
This study is looking at how the Chlamydia bacteria interact with our body's cells to understand how they survive and cause infections, which could help find better ways to treat these infections.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Nebraska Medical Center NIH-funded |
| Lab location | 1 site (Omaha, United States) |
| Project start | August 17, 2023 |
| Project end | December 31, 2025 |
| Funding year | 2024 |
| Award (this year) | $190,125 |
| NIH project number | 5R21AI178150-02 |
| Project ID | NIH-10909320 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include adults who have been diagnosed with Chlamydia infections or are at risk for such infections.
✕Less likely to help
Patients who are not affected by Chlamydia or do not have any related health issues may not benefit from this research.
What this research studies
This research investigates the interactions between the Chlamydia bacterium and its human host cells, focusing on the redoxome, which involves the balance of oxidation and reduction processes. By examining how Chlamydia adapts to live within human cells, the study aims to uncover mechanisms that contribute to the persistence and severity of infections. The research employs advanced techniques to analyze the bacterial and host cell responses, which could lead to new insights into treatment options for infections caused by this pathogen.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments and prevention strategies for Chlamydia infections and related complications.
How similar studies have gone: Previous research has shown promise in understanding bacterial interactions with host cells, suggesting that this approach could yield valuable insights.
Where this research is happening
-
University of Nebraska Medical Center
Omaha, United States Active
Researchers
- Principal investigator: Ouellette, Scot P — University of Nebraska Medical Center
- Study coordinator: Ouellette, Scot P
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.