Understanding how cells move together in groups
Revealing forces driving collective cell migration
This study is looking at how groups of cells move together, which is important for healing and fighting diseases like cancer, and it aims to create computer models that can help us understand how different signals affect this movement, ultimately leading to better treatments for conditions like chronic wounds and cancer.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Wisconsin-Madison NIH-funded |
| Lab location | 1 site (Madison, United States) |
| Project ID | NIH-11086789 on NIH RePORTER |
What this research studies
This research investigates the mechanics of collective cell migration, which is crucial for tissue development and disease progression. By combining biology, physics, and mathematics, the project aims to create computational models that predict how changes in biochemical signals affect cell movement. These models will help design new therapies to control cell migration, potentially improving treatments for chronic wounds and cancer. The research focuses on developing better methods to measure the forces that drive cell movement and how these forces interact with biological signals.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with chronic wounds or cancers where cell migration plays a significant role in disease progression.
Not a fit: Patients with conditions unrelated to cell migration or those not experiencing chronic wounds or cancer may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to innovative therapies that enhance wound healing and inhibit cancer cell spread.
How similar studies have performed: Previous research has shown promise in understanding cell migration mechanics, but this approach aims to enhance existing methods and could lead to novel insights.
Where this research is happening
Madison, United States
- University of Wisconsin-Madison — Madison, United States (Active)
Researchers
- Principal investigator: Notbohm, Jacob K — University of Wisconsin-Madison
- Study coordinator: Notbohm, Jacob K
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.