Understanding how cells create and maintain polarity during development
Official title: Polarity mechanisms driving complex morphogenesis
Funded at University of California, San Diego · NIH-10890707 · Data updated 2026-11-12
This study is looking at how plant cells organize themselves to grow and develop properly, using special imaging tools and genetic techniques to see how they change over time, which could help us learn more about how all cells work, including those in animals.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Diego NIH-funded |
| Lab location | 1 site (La Jolla, United States) |
| Project start | August 1, 2023 |
| Project end | July 31, 2028 |
| Funding year | 2024 |
| Award (this year) | $395,000 |
| NIH project number | 5R35GM150466-02 |
| Project ID | NIH-10890707 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation or benefit from this research would include individuals with developmental disorders or conditions related to cellular function and signaling.
✕Less likely to help
Patients with conditions unrelated to cellular polarity or developmental processes may not receive any benefit from this research.
What this research studies
This research investigates the mechanisms by which cells establish and maintain polarity, which is crucial for their development and function. By studying polarity pathways in developing plant tissues, the research aims to track individual cells over time and understand how they diversify during morphogenesis. The approach combines advanced imaging techniques with genetic analysis to reveal the molecular logic behind cell polarity. This work could provide insights applicable to both plant and animal cells, enhancing our understanding of cellular processes.
Why it matters
Potential benefit: If successful, this research could lead to breakthroughs in understanding developmental disorders and improve strategies for tissue engineering and regenerative medicine.
How similar studies have gone: Previous research has shown success in understanding cell polarity in simpler organisms, but this approach in complex plant tissues is relatively novel.
Where this research is happening
-
University of California, San Diego
La Jolla, United States Active
Researchers
- Principal investigator: Muroyama, Andrew D — University of California, San Diego
- Study coordinator: Muroyama, Andrew D
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.