Understanding how cancer spreads to the brain
Determine the mechanisms of acquired brain-tropism
This study is looking at how advanced cancers spread to the brain and aims to find ways to predict which patients might be at higher risk, so they can get better early care and treatment.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Stanford University NIH-funded |
| Lab location | 1 site (Stanford, United States) |
| Project ID | NIH-10925239 on NIH RePORTER |
What this research studies
This research investigates the mechanisms by which advanced cancers develop brain metastases, which affect a significant number of patients. It aims to identify predictive models that can help determine which patients are at high risk for developing brain metastases, thereby improving early detection and treatment outcomes. The study will utilize biological models to explore both the intrinsic features of tumors and the extrinsic characteristics of the brain environment that contribute to cancer spread. By analyzing these factors, the research seeks to enhance our understanding of brain cancer progression and treatment response.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients with advanced cancer who are at risk of developing brain metastases.
Not a fit: Patients with early-stage cancer or those whose cancer has not spread to the brain may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved early detection and treatment strategies for patients with advanced cancer at risk of brain metastases.
How similar studies have performed: Previous research has shown promise in understanding cancer metastasis, but this approach is exploring novel mechanisms that have not been extensively tested.
Where this research is happening
Stanford, United States
- Stanford University — Stanford, United States (Active)
Researchers
- Principal investigator: Ji, Hanlee P — Stanford University
- Study coordinator: Ji, Hanlee P
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.