Understanding how brain development issues affect movement and behavior in children
Official title: Molecular and Cellular Mechanisms of Cerebellar Dysfunction in Neurodevelopmental disorders
Funded at Baylor College of Medicine · NIH-10981992 · Data updated 2026-11-12
This study is looking at how problems in a part of the brain called the cerebellum might cause challenges in movement and thinking for people with conditions like autism, ADHD, and ataxia, so we can better understand what’s happening in the brain and help those affected.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Baylor College of Medicine NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project start | July 15, 2024 |
| Project end | June 30, 2029 |
| Funding year | 2024 |
| Award (this year) | $632,243 |
| NIH project number | 1R01NS134596-01A1 |
| Project ID | NIH-10981992 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include children diagnosed with neurodevelopmental disorders such as autism, ADHD, or ataxia.
✕Less likely to help
Patients with neurodevelopmental disorders not related to cerebellar dysfunction may not benefit from this research.
What this research studies
This research investigates the molecular and cellular mechanisms behind cerebellar dysfunction in neurodevelopmental disorders (NDDs) such as autism, ADHD, and ataxia. By examining the cerebellum, a brain region crucial for motor control and cognitive functions, the study aims to uncover how disruptions in its development can lead to various behavioral and sensory processing challenges. The research will utilize advanced techniques to analyze genetic factors and brain structure in affected individuals, providing insights into the underlying causes of these disorders.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and potential new treatments for children with neurodevelopmental disorders.
How similar studies have gone: Previous research has shown promising results in understanding the role of cerebellar dysfunction in neurodevelopmental disorders, indicating that this approach could yield valuable insights.
Where this research is happening
-
Baylor College of Medicine
Houston, United States Active
Researchers
- Principal investigator: Chao, Hsiao-Tuan — Baylor College of Medicine
- Study coordinator: Chao, Hsiao-Tuan
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.