Understanding how brain activity affects memory and learning in older adults
Official title: Examining the contributions of cognitive load and anterior cingulate cortex activity on striatal-hippocampal network coupling in age-related cognitive decline
Funded at University of Florida · NIH-10995272 · Data updated 2026-11-12
This study is looking at how the brain works and how it affects memory and learning in people aged 65 and older, to help tell the difference between normal aging and more serious memory problems, with the hope of improving diagnosis and treatment for age-related cognitive issues.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Florida NIH-funded |
| Lab location | 1 site (Gainesville, United States) |
| Project start | January 8, 2024 |
| Project end | January 7, 2027 |
| Funding year | 2025 |
| Award (this year) | $48,974 |
| NIH project number | 5F31AG082445-02 |
| Project ID | NIH-10995272 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals aged 65 and older who may be experiencing cognitive changes or are at risk for dementia.
✕Less likely to help
Patients under the age of 65 or those without any cognitive decline may not benefit from this research.
What this research studies
This research investigates how cognitive load and brain activity in specific areas influence memory and learning in individuals aged 65 and older. By examining the connections between different brain regions, particularly the anterior cingulate cortex and the striatal-hippocampal network, the study aims to differentiate between normal aging and pathological cognitive decline. Participants may undergo various cognitive tasks while their brain activity is monitored to identify changes in cognitive strategies as they age. The goal is to enhance diagnosis and treatment for age-related cognitive issues.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnostic tools and treatment strategies for older adults at risk of cognitive decline and dementia.
How similar studies have gone: Previous research has shown promising results in understanding cognitive changes in aging, suggesting that this approach could yield valuable insights.
Where this research is happening
-
University of Florida
Gainesville, United States Active
Researchers
- Principal investigator: Smith, Samantha Marie — University of Florida
- Study coordinator: Smith, Samantha Marie
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.