Understanding how ankle surgery affects lower limb movement

Integrating Musculoskeletal and Data-Driven Modeling to Understand the Biomechanical Sequelae of Syndesmotic Repair

NIH-funded research University of Florida · NIH-10897788

This study is looking at how fixing a specific ankle injury affects the way your whole leg moves and feels, especially for people who have had surgery to stabilize their ankle compared to those with healthy ankles, to help find better ways to treat and understand these injuries.

Quick facts

Grant typeFellowship grant
Study typeNIH-funded research
Funding institutionUniversity of Florida NIH-funded
Lab location1 site (Gainesville, United States)
Project IDNIH-10897788 on NIH RePORTER

What this research studies

This research investigates the impact of surgical repair of the ankle syndesmosis on the biomechanics of the entire lower limb. By comparing individuals with healthy, mobile fibulae to those with surgically immobilized fibulae, the study aims to identify how these repairs may lead to complications such as pain and osteoarthritis. The research employs advanced motion capture, force measurement, and electromyography techniques to gather data during various physical activities. The ultimate goal is to improve diagnostic and treatment strategies for syndesmotic injuries.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals who have recently undergone surgical repair of the ankle syndesmosis.

Not a fit: Patients who have not had ankle syndesmosis injuries or surgeries may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to better treatment options and improved outcomes for patients undergoing syndesmotic repair.

How similar studies have performed: While the specific approach of integrating biomechanical modeling with syndesmotic repair is novel, similar studies have shown success in understanding the biomechanics of other orthopedic injuries.

Where this research is happening

Gainesville, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.