Understanding how aging affects immune response and pathogen control
Official title: Admin Core
Funded at University of Minnesota · NIH-11053481 · Data updated 2026-11-12
This study is looking at how old cells in our bodies might affect how well our immune system fights off infections as we get older, and it's designed to help improve health for older adults.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Minnesota NIH-funded |
| Lab location | 1 site (Minneapolis, United States) |
| Project start | March 11, 2024 |
| Project end | February 28, 2029 |
| Funding year | 2025 |
| Award (this year) | $122,005 |
| NIH project number | 5P01AI172501-02 |
| Project ID | NIH-11053481 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are older adults or individuals with age-related immune dysfunction.
✕Less likely to help
Patients who are younger and do not have age-related immune issues may not benefit from this research.
What this research studies
This research focuses on the role of senescent cells in the immune system, particularly how their presence affects the body's ability to respond to infections as we age. The project involves a collaborative effort among experts in aging and immunology, utilizing advanced techniques to study immune function in aged animal models. By examining the interactions between aging and immune response, the research aims to uncover mechanisms that could lead to improved health outcomes for older adults.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for enhancing immune function in older patients, potentially reducing their susceptibility to infections.
How similar studies have gone: Previous research has shown promising results in understanding the impact of senescent cells on immune function, indicating that this approach has potential for significant findings.
Where this research is happening
-
University of Minnesota
Minneapolis, United States Active
Researchers
- Principal investigator: Jameson, Stephen C — University of Minnesota
- Study coordinator: Jameson, Stephen C
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.