Understanding heart issues after severe COVID-19
Official title: Immunologic basis of cardiac disease after severe COVID-19
Funded at University of Minnesota · NIH-11110480 · Data updated 2026-11-12
This project looks at how the immune system might cause heart problems in people who had severe COVID-19.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Minnesota NIH-funded |
| Lab location | 1 site (Minneapolis, United States) |
| Project start | July 1, 2022 |
| Project end | May 31, 2027 |
| Funding year | 2025 |
| Award (this year) | $662,793 |
| NIH project number | 5R01HL158756-04 |
| Project ID | NIH-11110480 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates are individuals who have experienced severe COVID-19 and are willing to participate in long-term follow-up, including blood draws and cardiac assessments.
✕Less likely to help
Patients who have not had severe COVID-19 or are not experiencing cardiac complications after COVID-19 may not directly benefit from this specific research.
What this research studies
Many people who get severe COVID-19 experience heart complications during their illness, and some continue to have heart and lung symptoms for months afterward, known as "Long COVID." This project wants to understand if the body's immune response to severe COVID-19 leads to inflammation and injury that can cause long-term heart scarring and problems with heart function. Researchers are collecting blood samples from patients with COVID-19 at different times, from admission to months after recovery. They will also perform heart imaging (CMR) and other tests on these participants to see how their hearts are doing over time.
Why it matters
Potential benefit: This work could help us better understand and potentially prevent or treat long-term heart problems in people who have recovered from severe COVID-19.
How similar studies have gone: While the long-term cardiac effects of COVID-19 are still being understood, this project builds on ongoing patient enrollment and aims to provide novel insights into the immune mechanisms involved.
Where this research is happening
-
University of Minnesota
Minneapolis, United States Active
Researchers
- Principal investigator: Shenoy, Chetan — University of Minnesota
- Study coordinator: Shenoy, Chetan
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.