Understanding heart function changes during pregnancy
Modeling cardiovascular function in pregnancy
This study is looking at how a woman's heart and blood flow change during pregnancy to keep both mom and baby healthy, and it aims to create a personalized model to help spot potential problems early, like high blood pressure, so that treatments can be better tailored to each woman's needs.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Oregon Health & Science University NIH-funded |
| Lab location | 1 site (Portland, United States) |
| Project ID | NIH-11061075 on NIH RePORTER |
What this research studies
This research investigates how a woman's heart and blood flow adapt during pregnancy, which is essential for the health of both the mother and the developing fetus. By creating a dynamic model that simulates cardiovascular function, the research aims to identify how these adaptations can go wrong, leading to complications like hypertension. The model will be personalized based on individual patient characteristics, allowing for tailored treatment strategies. This approach uses advanced mathematical techniques to predict outcomes and improve maternal and fetal health.
Who could benefit from this research
Good fit: Ideal candidates for this research are pregnant women who may be at risk for cardiovascular complications.
Not a fit: Patients who are not pregnant or those with pre-existing severe cardiovascular conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to personalized treatments that significantly improve maternal and fetal health during pregnancy.
How similar studies have performed: Similar research using dynamical modeling has shown promise in other areas of cardiovascular health, indicating potential for success in this novel application.
Where this research is happening
Portland, United States
- Oregon Health & Science University — Portland, United States (Active)
Researchers
- Principal investigator: Myatt, Leslie — Oregon Health & Science University
- Study coordinator: Myatt, Leslie
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.