Understanding heart function changes during pregnancy
Official title: Modeling cardiovascular function in pregnancy
Funded at Oregon Health & Science University · NIH-11061075 · Data updated 2026-11-12
This study is looking at how a woman's heart and blood flow change during pregnancy to keep both mom and baby healthy, and it aims to create a personalized model to help spot potential problems early, like high blood pressure, so that treatments can be better tailored to each woman's needs.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Oregon Health & Science University NIH-funded |
| Lab location | 1 site (Portland, United States) |
| Project start | April 1, 2024 |
| Project end | March 31, 2026 |
| Funding year | 2025 |
| Award (this year) | $200,789 |
| NIH project number | 5R21HD112740-02 |
| Project ID | NIH-11061075 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are pregnant women who may be at risk for cardiovascular complications.
✕Less likely to help
Patients who are not pregnant or those with pre-existing severe cardiovascular conditions may not benefit from this research.
What this research studies
This research investigates how a woman's heart and blood flow adapt during pregnancy, which is essential for the health of both the mother and the developing fetus. By creating a dynamic model that simulates cardiovascular function, the research aims to identify how these adaptations can go wrong, leading to complications like hypertension. The model will be personalized based on individual patient characteristics, allowing for tailored treatment strategies. This approach uses advanced mathematical techniques to predict outcomes and improve maternal and fetal health.
Why it matters
Potential benefit: If successful, this research could lead to personalized treatments that significantly improve maternal and fetal health during pregnancy.
How similar studies have gone: Similar research using dynamical modeling has shown promise in other areas of cardiovascular health, indicating potential for success in this novel application.
Where this research is happening
-
Oregon Health & Science University
Portland, United States Active
Researchers
- Principal investigator: Myatt, Leslie — Oregon Health & Science University
- Study coordinator: Myatt, Leslie
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.