Understanding different types of asthma in children using advanced data analysis
Official title: Integrating multi-omics data to understand asthma heterogeneity and endotypes
Funded at Brigham and Women's Hospital · NIH-10885340 · Data updated 2026-11-12
This study is looking at different types of asthma in kids by exploring how genetics and the environment affect their condition, with the goal of finding better ways to diagnose and treat asthma.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Brigham and Women's Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | September 1, 2024 |
| Project end | August 31, 2029 |
| Funding year | 2024 |
| Award (this year) | $177,403 |
| NIH project number | 1K01HL169756-01A1 |
| Project ID | NIH-10885340 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are children aged 0-11 years who have been diagnosed with asthma.
✕Less likely to help
Patients who do not have asthma or are older than 11 years may not benefit from this research.
What this research studies
This research investigates the various forms of asthma in children by analyzing complex biological data from multiple sources. It aims to identify distinct asthma types, known as endotypes, by examining genetic, epigenetic, and metabolomic factors. The study will utilize data from three cohorts of asthmatic children, focusing on how early-life factors and environmental exposures contribute to asthma development. By understanding these mechanisms, the research seeks to improve diagnosis and treatment strategies for asthma in children.
Why it matters
Potential benefit: If successful, this research could lead to more personalized and effective treatments for children with asthma.
How similar studies have gone: Previous research using multi-omics approaches has shown promise in understanding complex diseases, suggesting potential success for this innovative approach in asthma.
Where this research is happening
-
Brigham and Women's Hospital
Boston, United States Active
Researchers
- Principal investigator: Hecker, Julian Erik — Brigham and Women's Hospital
- Study coordinator: Hecker, Julian Erik
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.