Understanding different types of asthma in children using advanced data analysis
Integrating multi-omics data to understand asthma heterogeneity and endotypes
This study is looking at different types of asthma in kids by exploring how genetics and the environment affect their condition, with the goal of finding better ways to diagnose and treat asthma.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Brigham and Women's Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-10885340 on NIH RePORTER |
What this research studies
This research investigates the various forms of asthma in children by analyzing complex biological data from multiple sources. It aims to identify distinct asthma types, known as endotypes, by examining genetic, epigenetic, and metabolomic factors. The study will utilize data from three cohorts of asthmatic children, focusing on how early-life factors and environmental exposures contribute to asthma development. By understanding these mechanisms, the research seeks to improve diagnosis and treatment strategies for asthma in children.
Who could benefit from this research
Good fit: Ideal candidates for this research are children aged 0-11 years who have been diagnosed with asthma.
Not a fit: Patients who do not have asthma or are older than 11 years may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more personalized and effective treatments for children with asthma.
How similar studies have performed: Previous research using multi-omics approaches has shown promise in understanding complex diseases, suggesting potential success for this innovative approach in asthma.
Where this research is happening
Boston, United States
- Brigham and Women's Hospital — Boston, United States (Active)
Researchers
- Principal investigator: Hecker, Julian Erik — Brigham and Women's Hospital
- Study coordinator: Hecker, Julian Erik
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.