Understanding Daily Thinking Changes in Multiple Sclerosis

Optimizing detection and prediction of changes in cognitive function in multiple sclerosis with novel ambulatory assessment methods

['FUNDING_R01'] · UNIVERSITY OF MICHIGAN AT ANN ARBOR · NIH-11141113

This project uses a special smartphone app to help us learn more about how thinking and memory change in the daily lives of people with multiple sclerosis.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF MICHIGAN AT ANN ARBOR (nih funded)
Locations1 site (ANN ARBOR, UNITED STATES)
Trial IDNIH-11141113 on ClinicalTrials.gov

What this research studies

Multiple sclerosis often causes changes in thinking and memory, which can make daily life harder. Currently, we don't fully understand how these changes happen in everyday situations. This project uses a special smartphone app to track thinking skills like processing speed and memory as you go about your day. By collecting information directly from your lived environment, we hope to get a clearer picture of how cognitive challenges affect people with MS.

Who could benefit from this research

Good fit: Ideal participants would be individuals diagnosed with multiple sclerosis who are experiencing or interested in tracking changes in their thinking and memory.

Not a fit: Patients without multiple sclerosis or those not experiencing cognitive changes would likely not directly benefit from this specific research.

Why it matters

Potential benefit: If successful, this work could lead to better ways to detect, understand, and eventually help manage cognitive difficulties for people living with multiple sclerosis.

How similar studies have performed: This project applies advanced technology-assisted methods in a novel way to understand cognitive function in MS, building on general successes in mobile health technology.

Where this research is happening

ANN ARBOR, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: Autoimmune Diseases, Brain Diseases, Brain Disorders, CNS Diseases, CNS disorder

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.