Understanding brain function changes in people with HIV
Coupling of Inflammasome Cascades and Aberrant Neural Oscillatory Dynamics in NeuroHIV
This study is looking at how HIV impacts thinking and memory in people living with the virus, and it aims to find ways to help improve brain health by understanding the underlying causes.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Father Flanagan's Boys' Home NIH-funded |
| Lab location | 1 site (Boys Town, United States) |
| Project ID | NIH-11053565 on NIH RePORTER |
What this research studies
This research investigates how HIV affects brain function, particularly focusing on cognitive impairments that are common among individuals living with HIV. The study aims to explore the molecular pathways and inflammasome activation that contribute to these cognitive issues, using advanced neuroimaging techniques and biomarkers. By identifying the specific brain circuits involved, the research seeks to develop potential therapeutic strategies to improve cognitive health in people with HIV.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults over 21 years old who are living with HIV and experiencing cognitive impairments.
Not a fit: Patients who are not living with HIV or who do not exhibit cognitive impairments may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that improve cognitive function and quality of life for individuals living with HIV.
How similar studies have performed: Previous research has shown promise in understanding cognitive impairments in HIV, but this specific approach focusing on inflammasome pathways is relatively novel.
Where this research is happening
Boys Town, United States
- Father Flanagan's Boys' Home — Boys Town, United States (Active)
Researchers
- Principal investigator: Wilson, Tony W — Father Flanagan's Boys' Home
- Study coordinator: Wilson, Tony W
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.