Helping at-risk infants learn words by encouraging them to look at a speaker's mouth

Looking and Language (LoLa)

NIH-funded research Father Flanagan's Boys' Home · NIH-11468375

This project will teach infants who have an older autistic sibling to look at a speaker's mouth during play to help them pick up new words more easily.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionFather Flanagan's Boys' Home NIH-funded
Lab location1 site (Boys Town, United States)
Project IDNIH-11468375 on NIH RePORTER

What this research studies

If your infant joins, clinicians will use a play-based language program that sometimes moves the toy or object being named close to the speaker's mouth to encourage watching lips and faces. Children will be randomly assigned to receive this audiovisual cueing version or the same language program without the mouth-focused cue. The team will enroll about 60 infants who have an older sibling with autism and follow their language learning over time. Measures will track word learning and early language milestones to see which approach helps more.

Who could benefit from this research

Good fit: Infants who have an older sibling diagnosed with autism, especially those in the early stages of language development, are the ideal candidates.

Not a fit: Children without a family history of autism or older children beyond the early sensitive period for language may be unlikely to benefit from this specific pre-emptive approach.

Why it matters

Potential benefit: If successful, this approach could boost early word learning and improve longer-term language outcomes for infants at risk for autism.

How similar studies have performed: Short-term trainings using mouth-focused cues have increased word learning in autistic preschoolers for taught words, but applying this as a pre-emptive intervention in infants is a newer approach.

Where this research is happening

Boys Town, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Autistic Disorder
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.