Understanding brain development and behavior in infants with Down syndrome
The Infant Down Syndrome Brain and Behavior Study
This study is looking at how the brains of infants with Down syndrome develop and how that relates to the challenges they might face as they grow, with the hope of finding ways to better support their development.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Washington University NIH-funded |
| Lab location | 1 site (Saint Louis, United States) |
| Project ID | NIH-11001809 on NIH RePORTER |
What this research studies
This research investigates how brain development in infants with Down syndrome (DS) relates to their cognitive and behavioral challenges. By using advanced brain imaging techniques, the study aims to identify structural and functional differences in the brains of infants with DS compared to typically developing infants. The goal is to uncover the mechanisms behind developmental delays and to find biomarkers that could help tailor treatments for individuals with DS. This research will involve detailed assessments of brain function and structure in a cohort of infants diagnosed with DS.
Who could benefit from this research
Good fit: Ideal candidates for this research are infants diagnosed with Down syndrome, particularly those under the age of 12 months.
Not a fit: Patients who are older than 12 months or do not have a diagnosis of Down syndrome may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and personalized interventions for infants with Down syndrome, potentially enhancing their cognitive and behavioral outcomes.
How similar studies have performed: Previous research has shown promise in understanding brain development in other neurodevelopmental disorders, suggesting that this approach could yield valuable insights for Down syndrome as well.
Where this research is happening
Saint Louis, United States
- Washington University — Saint Louis, United States (Active)
Researchers
- Principal investigator: Marrus, Natasha — Washington University
- Study coordinator: Marrus, Natasha
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.