Understanding brain activity and decision-making in suicidal behavior

Cortical oscillatory dynamics and decision deficits in suicidal behavior - Resubmission

NIH-funded research University of Pittsburgh at Pittsburgh · NIH-11074526

This study is looking at how our brains make decisions during tough times, especially when people are feeling really stressed or uncertain, to better understand what leads to suicidal thoughts and actions, with the hope of finding ways to help prevent them.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of Pittsburgh at Pittsburgh NIH-funded
Lab location1 site (Pittsburgh, United States)
Project IDNIH-11074526 on NIH RePORTER

What this research studies

This research investigates the cognitive processes involved in suicidal behavior by utilizing advanced mathematical models and electrophysiological techniques. It aims to uncover how decision-making is affected during crises, particularly under high stress and uncertainty. By integrating decision neuroscience with computational modeling, the study seeks to provide a clearer understanding of the neural dynamics that contribute to suicidal thoughts and actions. This approach allows for a more mechanistic view of the factors influencing suicidal behavior, potentially leading to better prevention strategies.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals aged 21 and older who are experiencing suicidal thoughts or behaviors.

Not a fit: Patients who are not experiencing suicidal thoughts or behaviors may not receive benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved understanding and prevention strategies for suicidal behavior, ultimately saving lives.

How similar studies have performed: Other research has shown promise in using computational models and decision neuroscience to understand complex behaviors, suggesting that this approach could yield valuable insights.

Where this research is happening

Pittsburgh, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.