Understanding brain activity and decision-making in suicidal behavior
Official title: Cortical oscillatory dynamics and decision deficits in suicidal behavior - Resubmission
Funded at University of Pittsburgh at Pittsburgh · NIH-11074526 · Data updated 2026-11-12
This study is looking at how our brains make decisions during tough times, especially when people are feeling really stressed or uncertain, to better understand what leads to suicidal thoughts and actions, with the hope of finding ways to help prevent them.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pittsburgh at Pittsburgh NIH-funded |
| Lab location | 1 site (Pittsburgh, United States) |
| Project start | May 15, 2023 |
| Project end | April 30, 2028 |
| Funding year | 2025 |
| Award (this year) | $183,379 |
| NIH project number | 5K23MH130664-03 |
| Project ID | NIH-11074526 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals aged 21 and older who are experiencing suicidal thoughts or behaviors.
✕Less likely to help
Patients who are not experiencing suicidal thoughts or behaviors may not receive benefit from this research.
What this research studies
This research investigates the cognitive processes involved in suicidal behavior by utilizing advanced mathematical models and electrophysiological techniques. It aims to uncover how decision-making is affected during crises, particularly under high stress and uncertainty. By integrating decision neuroscience with computational modeling, the study seeks to provide a clearer understanding of the neural dynamics that contribute to suicidal thoughts and actions. This approach allows for a more mechanistic view of the factors influencing suicidal behavior, potentially leading to better prevention strategies.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and prevention strategies for suicidal behavior, ultimately saving lives.
How similar studies have gone: Other research has shown promise in using computational models and decision neuroscience to understand complex behaviors, suggesting that this approach could yield valuable insights.
Where this research is happening
-
University of Pittsburgh at Pittsburgh
Pittsburgh, United States Active
Researchers
- Principal investigator: Tsypes, Aliona — University of Pittsburgh at Pittsburgh
- Study coordinator: Tsypes, Aliona
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.