Understanding anxiety in Fragile X syndrome across childhood
Official title: Emergence, stability, and predictors of anxiety in Fragile X syndrome
Funded at University of South Carolina at Columbia · NIH-11412542 · Data updated 2026-11-12
A study follows children and young people with Fragile X syndrome to understand how anxiety starts, stays, and what predicts it over time.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of South Carolina at Columbia NIH-funded |
| Lab location | 1 site (Columbia, United States) |
| Project start | September 1, 2016 |
| Project end | May 31, 2028 |
| Funding year | 2026 |
| Award (this year) | $701,375 |
| NIH project number | 5R01MH107573-09 |
| Project ID | NIH-11412542 on NIH RePORTER |
Who could benefit from this research
✓Could help
Children, adolescents, and young adults with Fragile X syndrome who are part of the study’s age ranges and subgroups.
✕Less likely to help
Individuals outside the Fragile X spectrum or outside the study's age ranges may not directly benefit from the results.
What this research studies
This project tracks anxiety patterns in kids with Fragile X syndrome from early childhood through adolescence to see when anxiety first appears, how it develops, and what factors put someone at risk. Researchers will collect behavioral and developmental data, compare with other autism-related groups and typical peers, and look for early signals that predict later anxiety. The study builds on prior work and aims to clarify the developmental trajectory and consequences of anxiety in FXS to guide better support. Participation may involve regular assessments and collaboration with families over several years.
Why it matters
Potential benefit: Findings could lead to earlier identification and tailored interventions to reduce anxiety in children and young people with Fragile X syndrome.
How similar studies have gone: Past work showed early emergence and progression of anxiety in FXS, supporting continued study of its trajectory across development.
Where this research is happening
-
University of South Carolina at Columbia
Columbia, United States Active
Researchers
- Principal investigator: Hogan, Abigail Lee — University of South Carolina at Columbia
- Study coordinator: Hogan, Abigail Lee
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.