Understanding ADHD: how genes and brain networks shape attention and thinking in kids
Official title: Leveraging computational strategies to disentangle the genetic and neural underpinnings of ADHD and its associated cognitive systems
Funded at Massachusetts General Hospital · NIH-11379145 · Data updated 2026-11-12
This grant explores how genetics and brain systems contribute to ADHD and related thinking skills in children.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Massachusetts General Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | September 8, 2023 |
| Project end | July 31, 2028 |
| Funding year | 2026 |
| Award (this year) | $728,916 |
| NIH project number | 5R01MH130899-04 |
| Project ID | NIH-11379145 on NIH RePORTER |
Who could benefit from this research
✓Could help
Children and adolescents diagnosed with ADHD, as well as related youth whose cognitive and neural profiles are studied.
✕Less likely to help
Very young children or those without ADHD may not directly benefit from this research.
What this research studies
The project aims to untangle how genetic factors and brain networks influence attention and higher-order thinking in kids with ADHD. Researchers will use computational methods and large datasets to examine cognitive processes beyond memory and focus, under the NIMH framework. The work may involve imaging data, genetic information, and behavioral measures to map how these factors interact across development and daily functioning.
Why it matters
Potential benefit: If successful, findings could lead to more precise diagnoses and personalized strategies to support attention and learning in children with ADHD.
How similar studies have gone: Previous studies have linked cognitive traits to ADHD risk, but results vary and deeper mechanistic understanding remains. This project builds on existing evidence with a broader, integrative approach.
Where this research is happening
-
Massachusetts General Hospital
Boston, United States Active
Researchers
- Principal investigator: Ge, Tian — Massachusetts General Hospital
- Study coordinator: Ge, Tian
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.