Understanding addiction through animal behavior tests
Animal Models Core
This study is looking at how drugs like cocaine and heroin affect the behavior of mice and rats to better understand what happens in the brain during addiction, which could help us find better ways to treat people struggling with substance use.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Icahn School of Medicine at Mount Sinai NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-10934808 on NIH RePORTER |
What this research studies
This research focuses on using mice and rats to conduct a variety of behavioral tests that examine the effects of stimulants and opioids. By observing how these animals respond to drugs like cocaine and heroin, researchers aim to uncover the molecular and cellular mechanisms behind addiction. The study employs advanced techniques, including self-administration and relapse procedures, to gather comprehensive data. This information will help in understanding the complex nature of addiction and its underlying biological processes.
Who could benefit from this research
Good fit: Ideal candidates for benefiting from this research include individuals with a history of addiction to stimulants or opioids.
Not a fit: Patients who do not have substance use disorders or are not affected by addiction may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to new insights into addiction treatment and prevention strategies for patients struggling with substance use disorders.
How similar studies have performed: Previous research using animal models to study addiction has shown promising results, indicating that this approach is both valid and valuable in understanding addiction mechanisms.
Where this research is happening
New York, United States
- Icahn School of Medicine at Mount Sinai — New York, United States (Active)
Researchers
- Principal investigator: Kenny, Paul J. — Icahn School of Medicine at Mount Sinai
- Study coordinator: Kenny, Paul J.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.