Understanding addiction through animal behavior tests
Animal Models Core
['FUNDING_P01'] · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · NIH-11158912
This study is looking at how certain drugs, like stimulants and opioids, influence addiction by observing the behavior of mice and rats, which could help us understand what happens in the brain when someone struggles with addiction.
Quick facts
| Phase | ['FUNDING_P01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (nih funded) |
| Locations | 1 site (NEW YORK, UNITED STATES) |
| Trial ID | NIH-11158912 on ClinicalTrials.gov |
What this research studies
This research focuses on using various behavioral tests in mice and rats to explore how stimulants and opioids affect addiction. By employing a wide range of behavioral assays, the project aims to uncover the molecular and cellular mechanisms underlying addictive behaviors. The research includes both routine tests and advanced procedures that simulate self-administration and relapse, providing a comprehensive view of addiction. The findings will help establish connections between specific brain changes and addiction-related behaviors.
Who could benefit from this research
Good fit: Ideal candidates for benefiting from this research are individuals struggling with stimulant or opioid addiction.
Not a fit: Patients who do not have issues related to addiction or are not affected by stimulants or opioids may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new insights into addiction treatment and prevention strategies.
How similar studies have performed: Previous research using animal models has shown success in understanding addiction mechanisms, making this approach both validated and promising.
Where this research is happening
NEW YORK, UNITED STATES
- ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI — NEW YORK, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: KENNY, PAUL J. — ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI
- Study coordinator: KENNY, PAUL J.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: addictive disorder