Tiny Pancreas Particles for Type 1 Diabetes
Official title: Multimarker surface signatures of human islet derived extracellular vesicles
Funded at Meso Scale Diagnostics, LLC · NIH-11092903 · Data updated 2026-11-12
This work looks at tiny particles from the human pancreas to find new ways to detect, monitor, and treat Type 1 Diabetes.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Meso Scale Diagnostics, LLC NIH-funded |
| Lab location | 1 site (Rockville, United States) |
| Project start | September 22, 2022 |
| Project end | May 31, 2027 |
| Funding year | 2025 |
| Award (this year) | $691,014 |
| NIH project number | 5R01DK133861-04 |
| Project ID | NIH-11092903 on NIH RePORTER |
Who could benefit from this research
✓Could help
Patients living with or at risk for Type 1 Diabetes could ultimately benefit from the diagnostic and therapeutic advancements stemming from this research.
✕Less likely to help
Patients with conditions unrelated to Type 1 Diabetes or pancreatic function may not directly benefit from this specific research.
What this research studies
Our team is working to identify unique markers on the surface of tiny particles, called extracellular vesicles, that come from the different cells within the pancreas. We are developing new technologies to isolate and closely examine these specific particles. By observing changes in these particles, we hope to understand how they relate to the development and progression of Type 1 Diabetes. Ultimately, this could lead to new ways to find these pancreas-specific particles in a simple blood test.
Why it matters
Potential benefit: If successful, this research could lead to earlier and more accurate detection, better monitoring tools, and new treatment approaches for Type 1 Diabetes.
How similar studies have gone: Previous work has shown success in developing new techniques for screening and isolating these tiny particles, providing a strong foundation for this project.
Where this research is happening
-
Meso Scale Diagnostics, LLC
Rockville, United States Active
Researchers
- Principal investigator: Routenberg, David Aaron — Meso Scale Diagnostics, LLC
- Study coordinator: Routenberg, David Aaron
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.