Developing advanced tests to measure immune responses to influenza vaccines
A Flexible High-Throughput Immunological Assay to Support Next-Generation Influenza Vaccine Studies
['FUNDING_OTHER'] · MESO SCALE DIAGNOSTICS, LLC · NIH-10836539
This study is working on better tests to measure the antibodies people make after getting the flu vaccine or being infected with the flu, so we can understand how well the vaccine works and how it protects against different flu strains.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | MESO SCALE DIAGNOSTICS, LLC (nih funded) |
| Locations | 1 site (ROCKVILLE, UNITED STATES) |
| Trial ID | NIH-10836539 on ClinicalTrials.gov |
What this research studies
This research focuses on creating improved assays to measure the antibodies generated in individuals following influenza infection or vaccination. By utilizing high-throughput multiplexed formats, the study aims to develop tests that can efficiently assess both total antibody responses and the specific antibodies that provide protection against the virus. The assays will leverage the Meso Scale Diagnostics® electrochemiluminescence platform, allowing for simultaneous measurement of antibodies against various influenza strains, which could enhance our understanding of vaccine efficacy and cross-protection.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals who have recently been vaccinated against influenza or have experienced an influenza infection.
Not a fit: Patients who are not involved in influenza vaccination or infection may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective influenza vaccines by providing better insights into immune responses.
How similar studies have performed: Similar approaches have shown success in the qualification of vaccines for other diseases, indicating a promising potential for this novel assay development.
Where this research is happening
ROCKVILLE, UNITED STATES
- MESO SCALE DIAGNOSTICS, LLC — ROCKVILLE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: SIGAL, GEORGE B — MESO SCALE DIAGNOSTICS, LLC
- Study coordinator: SIGAL, GEORGE B
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.