Testing new methods for editing genes in mouse models
Official title: Genome Editing and Biological Effects Testing Section
Funded at Baylor College of Medicine · NIH-10917291 · Data updated 2026-11-12
This study is working on new ways to edit genes and deliver those changes safely, using mice to see how well these methods work, which could eventually help improve treatments for genetic disorders that affect people like you.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Baylor College of Medicine NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project start | December 1, 2023 |
| Project end | November 30, 2028 |
| Funding year | 2025 |
| Award (this year) | $364,556 |
| NIH project number | 5U42OD035581-02 |
| Project ID | NIH-10917291 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for benefiting from this research are individuals with genetic disorders that may be targeted by genome editing therapies.
✕Less likely to help
Patients with conditions not related to genetic disorders or those who do not respond to gene therapies may not receive benefits from this research.
What this research studies
This research focuses on developing and testing innovative genome editing tools and delivery systems using mouse models. The project aims to create a centralized resource that provides researchers with access to standardized testing procedures for evaluating the effectiveness and safety of these genome editing technologies. By utilizing advanced techniques, the research will assess how well these tools work in various tissues and their potential health impacts. Patients may benefit indirectly as the findings could lead to improved gene therapies for genetic disorders.
Why it matters
Potential benefit: If successful, this research could enhance the safety and effectiveness of gene therapies for patients with genetic disorders.
How similar studies have gone: Previous research has shown promising results in genome editing approaches, indicating potential for significant advancements in this area.
Where this research is happening
-
Baylor College of Medicine
Houston, United States Active
Researchers
- Principal investigator: Lagor, William Raymond — Baylor College of Medicine
- Study coordinator: Lagor, William Raymond
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.