NIH-funded research R01 grant

Telemedicine-Delivered Prolonged Exposure Therapy for PTSD in People with Opioid Use Disorder

Official title: Novel Telemedicine-Delivered Prolonged Exposure Therapy for Treating PTSD in Individuals with OUD

Funded at University of Vermont & St Agric College · NIH-11330257 · Data updated 2026-11-12

A new telemedicine-based therapy program aims to help adults with opioid use disorder who also have PTSD feel better and stay in treatment.

More PTSD research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Vermont & St Agric College
NIH-funded
Lab location1 site (Burlington, United States)
Project startJuly 15, 2023
Project endMay 31, 2028
Funding year2026
Award (this year)$690,686
NIH project number5R01DA057308-04
Project IDNIH-11330257 on NIH RePORTER

Who could benefit from this research

Could help

Adults 21 years or older with opioid use disorder, PTSD symptoms, and access to telemedicine options, including those on buprenorphine maintenance.

Less likely to help

Individuals without PTSD symptoms or without access to telemedicine might not benefit.

What this research studies

This project tests a telemedicine version of Prolonged Exposure therapy to treat PTSD in adults who are on medication for opioid use disorder. It builds on previous findings that PE can help PTSD but attendance is a barrier, and that adding financial incentives may improve engagement. The study compares standard care, PE, and PE with attendance incentives, focusing on reducing PTSD symptoms and potentially reducing illicit drug use. Researchers will use a novel online platform to reach patients who may have limited access to in-person care. If successful, the approach could expand access to effective PTSD treatment for people with opioid use disorder.

Why it matters

Potential benefit: If successful, patients could experience reduced PTSD symptoms and better adherence to opioid-use treatment, potentially improving overall health and stability.

How similar studies have gone: Early data suggest that telemedicine-delivered PE with attendance incentives can improve therapy attendance and PTSD symptoms, warranting a definitive evaluation.

Where this research is happening

  • University of Vermont & St Agric College
    Burlington, United States
    Active

Researchers

  • Principal investigator: Peck, Kelly R. — University of Vermont & St Agric College
  • Study coordinator: Peck, Kelly R.

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.