NIH-funded research R01 grant

Stepped care digital program to keep weight off after loss

Official title: Stepped Care for Weight Loss Maintenance

Funded at Johns Hopkins University · NIH-11374489 · Data updated 2026-11-12

A Johns Hopkins team is testing a digital, stepped-care approach to help people keep at least 5% of their weight off after an initial loss.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionJohns Hopkins University
NIH-funded
Lab location1 site (Baltimore, United States)
Project startSeptember 5, 2023
Project endJune 30, 2028
Funding year2026
Award (this year)$419,313
NIH project number5R01NR020197-04
Project IDNIH-11374489 on NIH RePORTER

Who could benefit from this research

Could help

Adults with obesity who have already achieved a weight loss of more than 5% after 16 weeks.

Less likely to help

Individuals who have not yet started losing weight or who cannot use digital health tools may receive little to no benefit.

What this research studies

After an initial 16-week weight loss phase, adults with obesity will be followed for a year to see if a digital, stepped-care maintenance program helps prevent weight regain. Participants are randomized to daily self-monitoring with digital tools, monthly maintenance education, or access to a personalized text-message supported program that adjusts the level of support over time. The study uses remote monitoring of weight, activity, and diet, with automated reminders to support adherence. The goal is to develop a patient-centered maintenance strategy that is easy to use in real life and reduces relapse.

Why it matters

Potential benefit: If successful, this program could help people maintain meaningful weight loss with less in-person counseling.

How similar studies have gone: Prior research suggests remote, tailored support can aid weight maintenance, but this stepped-care approach in a digital format is still being tested.

Where this research is happening

  • Johns Hopkins University
    Baltimore, United States
    Active

Researchers

  • Principal investigator: Chao, Ariana Marie — Johns Hopkins University
  • Study coordinator: Chao, Ariana Marie

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.