NIH-funded research NIH-funded research

STAR Center: Stress, Trauma, and Resilience and Heart Health

Official title: COBRE for Stress, Trauma and Resilience (STAR)

Funded at Miriam Hospital · NIH-11336535 · Data updated 2026-11-12

A nationwide program helps adults who faced childhood stress build healthier hearts and lives by studying how early adversity affects cardiovascular disease and by developing ways to prevent it.

More Resilience research and trials

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionMiriam Hospital
NIH-funded
Lab location1 site (Providence, United States)
Project startSeptember 15, 2021
Project endJuly 31, 2031
Funding year2026
Award (this year)$2,257,336
NIH project number2P20GM139767-06
Project IDNIH-11336535 on NIH RePORTER

Who could benefit from this research

Could help

Adults with a history of childhood stress or trauma who are at risk for or have cardiovascular disease.

Less likely to help

Individuals without a history of childhood adversity or those not at risk for cardiovascular disease may not directly benefit.

What this research studies

This NIH grant supports a center that brings together researchers to understand how childhood stress leads to heart disease later in life. It funds early-career scientists and clinicians to develop new approaches and pursue independent research, with mentorship from senior NIH scientists. The goal is to create effective interventions that improve long-term health outcomes for adults who experienced adversity. The center has already generated substantial published work and grants, and Phase 2 aims to expand capacity and impact across the field.

Why it matters

Potential benefit: If successful, patients with a history of childhood adversity could receive better prevention and treatment strategies for cardiovascular disease.

How similar studies have gone: The program builds on a strong track record of STAR COBRE work, with many publications and grants already achieved.

Where this research is happening

  • Miriam Hospital
    Providence, United States
    Active

Researchers

  • Principal investigator: Stroud, Laura R — Miriam Hospital
  • Study coordinator: Stroud, Laura R

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.