NIH-funded research R01 grant

Sleep problems and opioid use after adolescent surgery

Official title: Sleep deficiency and opioid use/misuse in adolescents following surgery

Funded at Stanford University · NIH-11406197 · Data updated 2026-11-12

This project looks at how sleep problems after surgery may influence whether teens start using prescribed opioids in risky ways.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionStanford University
NIH-funded
Lab location1 site (Stanford, United States)
Project startSeptember 10, 2023
Project endAugust 31, 2028
Funding year2026
Award (this year)$596,776
NIH project number5R01HL166337-04
Project IDNIH-11406197 on NIH RePORTER

Who could benefit from this research

Could help

Adolescents undergoing surgery who are prescribed opioids postoperatively and experience sleep disturbances.

Less likely to help

Teens without sleep problems or those not prescribed opioids after surgery may have less direct benefit.

What this research studies

After adolescent surgery, sleep problems may contribute to opioid misuse. The study aims to identify which sleep issues and related factors are most linked to early misuse and to understand the behavioral and psychological mechanisms involved. Using data from Stanford, researchers will examine how perioperative sleep disturbances relate to opioid use and test potential pathways such as pain and mood. The goal is to identify opportunities for early intervention to reduce misuse risk in teens recovering from surgery.

Why it matters

Potential benefit: If successful, the research could lead to strategies that prevent opioid misuse in teens after surgery by addressing sleep health.

How similar studies have gone: Preliminary work shows a link between sleep problems and opioid use, but deeper, mechanism-focused studies are needed.

Where this research is happening

  • Stanford University
    Stanford, United States
    Active

Researchers

  • Principal investigator: Groenewald, Cornelius Botha — Stanford University
  • Study coordinator: Groenewald, Cornelius Botha

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.