NIH-funded research R01 grant

Sleep extension to boost weight loss in young adults

Official title: Sleep Extension: A Novel Intervention for Weight Loss in Young Adults

Funded at University of Chicago · NIH-11398984 · Data updated 2026-11-12

A study tests whether adding more sleep to a calorie- and activity‑focused weight loss program helps overweight young adults lose more weight.

More Weight Loss research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Chicago
NIH-funded
Lab location1 site (Chicago, United States)
Project startSeptember 15, 2023
Project endAugust 31, 2028
Funding year2026
Award (this year)$705,766
NIH project number5R01DK136214-04
Project IDNIH-11398984 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates are overweight young adults (around 18–25) who habitually sleep less than 6.5 hours per night and are willing to follow a diet and activity plan.

Less likely to help

Individuals who already consistently sleep 7+ hours or who cannot commit to the sleep extension component may not benefit.

What this research studies

Young adults who sleep less than 6.5 hours a night and are overweight will be recruited to see if extending sleep, in addition to diet and physical activity guidance, leads to better weight loss. Participants will be randomly assigned to either a standard lifestyle intervention or the same program plus structured sleep extension strategies. The study uses real‑world settings and tracking (like accelerometers and a smartphone app) to monitor sleep, activity, and diet. Results could show whether sleep duration is a key lever to enhance weight loss in similar programs.

Why it matters

Potential benefit: If successful, the approach could improve weight loss outcomes for young adults by including a practical sleep extension component.

How similar studies have gone: Preliminary work suggests sleep extension can reduce energy intake and support weight loss, but this trial is among the first to test its impact within a structured lifestyle program.

Where this research is happening

  • University of Chicago
    Chicago, United States
    Active

Researchers

  • Principal investigator: Tasali, Esra — University of Chicago
  • Study coordinator: Tasali, Esra

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.