NIH-funded research R01 grant

Sleep and insomnia treatment to help heavy drinkers reduce alcohol use

Official title: Sleep as a Mechanism of Change in Alcohol Use Outcomes among Heavy-Drinking Adults

Funded at University of Missouri-Columbia · NIH-11384848 · Data updated 2026-11-12

This project tests whether treating insomnia with CBT-I can help adults who drink heavily cut down on alcohol use and improve heart and sleep health.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Missouri-Columbia
NIH-funded
Lab location1 site (Columbia, United States)
Project startSeptember 1, 2023
Project endAugust 31, 2028
Funding year2026
Award (this year)$431,619
NIH project number5R01AA030525-04
Project IDNIH-11384848 on NIH RePORTER

Who could benefit from this research

Could help

Adults 21 years and older who drink heavily and have insomnia and are willing to participate in CBT-I or a waitlist control.

Less likely to help

Individuals without insomnia or with different sleep or alcohol-use patterns may not benefit.

What this research studies

Heavy drinking affects many adults and insomnia is common among those at risk. The study will follow adults with heavy drinking and insomnia, comparing Cognitive Behavioral Therapy for Insomnia (CBT-I) to a waitlist control over five years. Researchers will track sleep, drinking, mood, and cardiovascular indicators at several time points during and after treatment to understand how sleep changes relate to alcohol outcomes. If CBT-I helps reduce drinking and improves health, it could offer a practical way to engage people in care who are reluctant to seek mental health treatment.

Why it matters

Potential benefit: If successful, improving sleep may reduce alcohol use and lower cardiovascular risk for heavy-drinking adults with insomnia.

How similar studies have gone: Past work shows CBT-I can improve sleep and may influence alcohol-related outcomes, but combining sleep treatment with alcohol outcomes in this way is an advancing area.

Where this research is happening

  • University of Missouri-Columbia
    Columbia, United States
    Active

Researchers

  • Principal investigator: Miller, Mary Elizabeth — University of Missouri-Columbia
  • Study coordinator: Miller, Mary Elizabeth

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.