NIH-funded research NIH-funded research

Shared benchmarking specimens for human virome research

Official title: Developing Shared Benchmarking Specimens for HVP Research: Supplement to: The Oro-Respiratory-Gut Virome Axis over Space and Time - 1U54AG089323

Funded at University of Pennsylvania · NIH-11529208 · Data updated 2026-11-12

Aimed at creating standard, well‑characterized samples to compare different virus-detection methods used in human virome research.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of Pennsylvania
NIH-funded
Lab location1 site (Philadelphia, United States)
Project startFebruary 1, 2025
Project endJanuary 31, 2030
Funding year2026
Award (this year)$245,074
NIH project number3U54AG089323-02S1
Project IDNIH-11529208 on NIH RePORTER

Who could benefit from this research

Could help

Not applicable; this grant is about standard materials and data methods for virome research rather than direct patient participation.

Less likely to help

No direct patient participation is involved in this benchmarking effort.

What this research studies

This project provides standardized benchmarking specimens to harmonize results across centers studying the human virome. It focuses on understanding how different sequencing approaches and amplification methods bias the data, so researchers can compare results more reliably. By sharing a model community of quantified viruses, it helps labs calibrate their assays and integrate data from diverse methods, ultimately improving our map of human-associated viruses.

Why it matters

Potential benefit: If successful, this work could improve consistency and accuracy in virome studies, helping researchers better identify viruses related to health and disease.

How similar studies have gone: A validated model community of eight quantified viruses has already been shared with 11 labs, demonstrating feasibility and utility.

Where this research is happening

  • University of Pennsylvania
    Philadelphia, United States
    Active

Researchers

  • Principal investigator: Collman, Ronald G — University of Pennsylvania
  • Study coordinator: Collman, Ronald G

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.