Reducing prostate cancer radiotherapy toxicity through genes and technology

Who could benefit from this research

What this research studies

This project looks for biomarkers in patients receiving radiotherapy for localized prostate cancer to predict who might experience harmful side effects. It focuses on genetic markers, like germ-line variations, and how they relate to radiation-related toxicity. The team aims to connect these biomarkers with mechanism-based strategies to prevent or lessen adverse effects, with a goal of personalizing treatment. Participants would contribute samples and clinical data to help identify predictive signals that could guide future care. The work is centered on improving quality of life for patients after radiotherapy by reducing late toxicity.

Why it matters

Where this research is happening

• University of California Los Angeles
  Los Angeles, United States Active

Researchers

• Principal investigator: Kishan, Amar U — University of California Los Angeles
• Study coordinator: Kishan, Amar U

Related research

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About this research

1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.