READD-ADSP: Building a genetic resource to understand Alzheimer's in diverse populations
Official title: Recruitment and Retention for Alzheimer's Disease Diversity Genetic Cohorts in the ADSP (READD-ADSP)
Funded at University of Miami School of Medicine · NIH-11563824 · Data updated 2026-11-12
This NIH grant aims to create a large, diverse genetic resource to study why Alzheimer's affects people differently across African, African American, and Hispanic/Latino populations.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Miami School of Medicine NIH-funded |
| Lab location | 1 site (Coral Gables, United States) |
| Project start | July 1, 2022 |
| Project end | June 30, 2027 |
| Funding year | 2026 |
| Award (this year) | $42,995 |
| NIH project number | 3U19AG074865-05S4 |
| Project ID | NIH-11563824 on NIH RePORTER |
Who could benefit from this research
✓Could help
Individuals of African, African American, or Hispanic/Latino ancestry who may contribute clinical, phenotypic, or genetic data to the study after appropriate consent.
✕Less likely to help
People not matching these ancestry groups or without involvement in a genetic study would not directly benefit.
What this research studies
The project will recruit and genotype about 13,000 individuals from Africa, African American, and Hispanic/Latino groups to study the genetic factors contributing to Alzheimer's disease. Data on clinical features, phenotypes, and genetics will be harmonized with existing studies to enable broader comparisons. Two hypothesis-driven projects will use the resource to explore how ancestry and environment shape genetic risk for Alzheimer’s in these populations. The work is designed to improve our understanding of disease mechanisms and move toward more inclusive research and potential future therapies.
Why it matters
Potential benefit: By expanding genetic understanding across diverse groups, this work could lead to more accurate risk assessment and tailored approaches for prevention and treatment in populations historically underrepresented in research.
How similar studies have gone: Previous studies have shown that including diverse populations can reveal unique risk factors and improve generalizability of findings.
Where this research is happening
-
University of Miami School of Medicine
Coral Gables, United States Active
Researchers
- Principal investigator: Pericak-Vance, Margaret a. — University of Miami School of Medicine
- Study coordinator: Pericak-Vance, Margaret a.
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.